BDBM30647 MLS-0291694.0001::N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)ethanesulfonamide::N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]ethanesulfonamide::N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]ethanesulfonamide::cid_16194594

SMILES: CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1

InChI Key: InChIKey=HPLPIUZUPXOANW-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM30647 (MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...) Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1 Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM30647 (MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...) Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1 Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM30647 (MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...) Show SMILES CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1 Show InChI InChI=1S/C14H13N3O2S2/c1-2-21(18,19)17-11-7-5-10(6-8-11)13-16-12-4-3-9-15-14(12)20-13/h3-9,17H,2H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.29E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair