new BindingDB logo
myBDB logout

BDBM306676 (+-)-N-[(6-amino-2,4-dimethyl- pyridin-3-yl)methyl]-5,8- dihydroxy-19-oxa-6,7- diazapentacyclo [10.6.1.02,11.04,9.013,18] nonadeca-2(11),3,5,7,9,13,15,17- octaene-15-carboxamide::US10144746, Compound 320

SMILES: Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc2c(O)nnc(O)c2cc31

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306676   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))
BDBM306676
PNG
((+-)-N-[(6-amino-2,4-dimethyl- pyridin-3-yl)methyl...)
Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc2c(O)nnc(O)c2cc31
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0n/an/an/an/an/an/a



Global Blood Therapeutics, Inc.

US Patent




US Patent US10144746 (2018)


BindingDB Entry DOI: 10.7270/Q2J38VNH
More data for this
Ligand-Target Pair