BDBM306703 (1S,8R)-N-[(4- carbamimidoylphenyl) methyl]-11,12-diethyl- 15-oxatetracyclo [6.6.1.02,7.09,14] pentadeca- 2,4,6,9(14),10,12- hexaene-4-carboxamide::US10144746, Compound 392
SMILES: CCc1cc2[C@@H]3O[C@H](c2cc1CC)c1cc(ccc31)C(=O)NCc1ccc(cc1)C(N)=N
InChI Key: InChIKey=XROGSPJLCQLFQP-RPBOFIJWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Plasma kallikrein (Homo sapiens (Human)) | BDBM306703 ((1S,8R)-N-[(4- carbamimidoylphenyl) methyl]-11,12-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Global Blood Therapeutics, Inc. US Patent | Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w... | US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH | |||||||||||
More data for this Ligand-Target Pair |