BDBM307514 US10150740, Example 10

SMILES: COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCN1CCOCC1

InChI Key: InChIKey=RTXVTBJAKQOJTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus polyprotein (Hepatitis C virus (HCV))	BDBM307514 (US10150740, Example 10) Show SMILES COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCN1CCOCC1 Show InChI InChI=1S/C24H31N3O6/c1-16(2)13-26-14-17-10-23(33-9-6-25-4-7-32-8-5-25)22(31-3)11-18(17)20-12-21(28)19(24(29)30)15-27(20)26/h10-12,15-16H,4-9,13-14H2,1-3H3,(H,29,30)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells (Acs et al. Proc Natl Acad Sci USA, 84, (1987), 4641-4), a constitutively HBV-expressing cell line were cultured in DMEM+Glutamax-I ...				US Patent US10150740 (2018) BindingDB Entry DOI: 10.7270/Q2RN39WH
					More data for this Ligand-Target Pair