BDBM307518 US10150740, Example 14

SMILES: COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCCCCNC(=O)OC(C)(C)C

InChI Key: InChIKey=RWRQSSIUVTYZMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus polyprotein (Hepatitis C virus (HCV))	BDBM307518 (US10150740, Example 14) Show SMILES COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCCCCNC(=O)OC(C)(C)C Show InChI InChI=1S/C28H39N3O7/c1-18(2)15-30-16-19-12-25(37-11-9-7-8-10-29-27(35)38-28(3,4)5)24(36-6)13-20(19)22-14-23(32)21(26(33)34)17-31(22)30/h12-14,17-18H,7-11,15-16H2,1-6H3,(H,29,35)(H,33,34)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells (Acs et al. Proc Natl Acad Sci USA, 84, (1987), 4641-4), a constitutively HBV-expressing cell line were cultured in DMEM+Glutamax-I ...				US Patent US10150740 (2018) BindingDB Entry DOI: 10.7270/Q2RN39WH
					More data for this Ligand-Target Pair