BDBM307550 N-(2-cyanopropan-2-yl)-5-(6-ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-5-yl)-2-(methoxy-d3)nicotinamide::US10150747, Example 17

SMILES: CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cnc(OC)c(c1)C(=O)NC(C)(C)C#N)-c1ccc(F)cc1

InChI Key: InChIKey=RFDYTZLABBIWRF-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307550 (N-(2-cyanopropan-2-yl)-5-(6-ethoxy-2-(4-fluorophen...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cnc(OC)c(c1)C(=O)NC(C)(C)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C29H27FN4O5/c1-6-38-22-13-23-20(24(27(36)32-4)25(39-23)16-7-9-18(30)10-8-16)12-19(22)17-11-21(28(37-5)33-14-17)26(35)34-29(2,3)15-31/h7-14H,6H2,1-5H3,(H,32,36)(H,34,35)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307550 (N-(2-cyanopropan-2-yl)-5-(6-ethoxy-2-(4-fluorophen...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cnc(OC)c(c1)C(=O)NC(C)(C)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C29H27FN4O5/c1-6-38-22-13-23-20(24(27(36)32-4)25(39-23)16-7-9-18(30)10-8-16)12-19(22)17-11-21(28(37-5)33-14-17)26(35)34-29(2,3)15-31/h7-14H,6H2,1-5H3,(H,32,36)(H,34,35)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.84	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair