BDBM307558 5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamoyl)-4-methoxyphenyl)-2-(4-fluorophenyl)-N-methyl-6-propoxybenzofuran-3-carboxamide::US10150747, Example 25

SMILES: CCCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(OC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1

InChI Key: InChIKey=GQYCNFLAAFLJEN-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307558 (5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...) Show SMILES CCCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(OC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H31FN4O6/c1-6-13-41-25-16-26-22(27(30(39)34-4)28(43-26)18-7-10-20(33)11-8-18)15-21(25)19-9-12-24(40-5)23(14-19)29(38)36-32(2,3)31-35-17-42-37-31/h7-12,14-17H,6,13H2,1-5H3,(H,34,39)(H,36,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.23	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307558 (5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...) Show SMILES CCCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(OC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H31FN4O6/c1-6-13-41-25-16-26-22(27(30(39)34-4)28(43-26)18-7-10-20(33)11-8-18)15-21(25)19-9-12-24(40-5)23(14-19)29(38)36-32(2,3)31-35-17-42-37-31/h7-12,14-17H,6,13H2,1-5H3,(H,34,39)(H,36,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.48	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair