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SMILES: O=C(N1CCC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=LGPRRHAWYZPBBC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307627 (5-(azetidine-1- carbonyl)-2-(6-(4- cyclopropyl-4H-...) Show SMILES O=C(N1CCC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C22H20N6O2/c29-21(26-9-2-10-26)14-5-8-17-15(11-14)12-27(22(17)30)19-4-1-3-18(24-19)20-25-23-13-28(20)16-6-7-16/h1,3-5,8,11,13,16H,2,6-7,9-10,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307627 (5-(azetidine-1- carbonyl)-2-(6-(4- cyclopropyl-4H-...) Show SMILES O=C(N1CCC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C22H20N6O2/c29-21(26-9-2-10-26)14-5-8-17-15(11-14)12-27(22(17)30)19-4-1-3-18(24-19)20-25-23-13-28(20)16-6-7-16/h1,3-5,8,11,13,16H,2,6-7,9-10,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair