null

SMILES: O=C(N1CC2CCC(C1)O2)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=RNPBXAXAFOFOJK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307629 (5-((1R,5S)-8-oxa-3- azabicyclo[3.2.1] octane-3-car...) Show SMILES O=C(N1CC2CCC(C1)O2)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 |TLB:1:2:5.6:9| Show InChI InChI=1S/C25H24N6O3/c32-24(29-12-18-7-8-19(13-29)34-18)15-4-9-20-16(10-15)11-30(25(20)33)22-3-1-2-21(27-22)23-28-26-14-31(23)17-5-6-17/h1-4,9-10,14,17-19H,5-8,11-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307629 (5-((1R,5S)-8-oxa-3- azabicyclo[3.2.1] octane-3-car...) Show SMILES O=C(N1CC2CCC(C1)O2)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 |TLB:1:2:5.6:9| Show InChI InChI=1S/C25H24N6O3/c32-24(29-12-18-7-8-19(13-29)34-18)15-4-9-20-16(10-15)11-30(25(20)33)22-3-1-2-21(27-22)23-28-26-14-31(23)17-5-6-17/h1-4,9-10,14,17-19H,5-8,11-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair