null

SMILES: CO[C@@H]1CCN(C1)C(=O)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=USVFCIIDRAKQCD-GOSISDBHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307630 ((R)-2-(6-(4- cyclopropyl-4H- 1,2,4-triazol-3- yl)p...) Show SMILES CO[C@@H]1CCN(C1)C(=O)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 |r| Show InChI InChI=1S/C24H24N6O3/c1-33-18-9-10-28(13-18)23(31)15-5-8-19-16(11-15)12-29(24(19)32)21-4-2-3-20(26-21)22-27-25-14-30(22)17-6-7-17/h2-5,8,11,14,17-18H,6-7,9-10,12-13H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307630 ((R)-2-(6-(4- cyclopropyl-4H- 1,2,4-triazol-3- yl)p...) Show SMILES CO[C@@H]1CCN(C1)C(=O)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1 |r| Show InChI InChI=1S/C24H24N6O3/c1-33-18-9-10-28(13-18)23(31)15-5-8-19-16(11-15)12-29(24(19)32)21-4-2-3-20(26-21)22-27-25-14-30(22)17-6-7-17/h2-5,8,11,14,17-18H,6-7,9-10,12-13H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair