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SMILES: Cc1ccc(cn1)-c1ccc2CN(C(=O)c2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=UAGHSQBOKUDAIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307650 (2-(6-(4-cyclopropyl- 4H-1,2,4-triazol-3- yl)pyridi...) Show SMILES Cc1ccc(cn1)-c1ccc2CN(C(=O)c2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C24H20N6O/c1-15-5-6-17(12-25-15)16-7-8-18-13-29(24(31)20(18)11-16)22-4-2-3-21(27-22)23-28-26-14-30(23)19-9-10-19/h2-8,11-12,14,19H,9-10,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307650 (2-(6-(4-cyclopropyl- 4H-1,2,4-triazol-3- yl)pyridi...) Show SMILES Cc1ccc(cn1)-c1ccc2CN(C(=O)c2c1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C24H20N6O/c1-15-5-6-17(12-25-15)16-7-8-18-13-29(24(31)20(18)11-16)22-4-2-3-21(27-22)23-28-26-14-30(23)19-9-10-19/h2-8,11-12,14,19H,9-10,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair