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SMILES: O=C1N(Cc2ccc(cc12)-n1cc(nn1)C1CC1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=JEIPPRMBPRWCQA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307670 (6-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-2-(6-(4-cy...) Show SMILES O=C1N(Cc2ccc(cc12)-n1cc(nn1)C1CC1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C23H20N8O/c32-23-18-10-17(31-12-20(26-28-31)14-4-5-14)7-6-15(18)11-29(23)21-3-1-2-19(25-21)22-27-24-13-30(22)16-8-9-16/h1-3,6-7,10,12-14,16H,4-5,8-9,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q2125VQ8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM307670 (6-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-2-(6-(4-cy...) Show SMILES O=C1N(Cc2ccc(cc12)-n1cc(nn1)C1CC1)c1cccc(n1)-c1nncn1C1CC1 Show InChI InChI=1S/C23H20N8O/c32-23-18-10-17(31-12-20(26-28-31)14-4-5-14)7-6-15(18)11-29(23)21-3-1-2-19(25-21)22-27-24-13-30(22)16-8-9-16/h1-3,6-7,10,12-14,16H,4-5,8-9,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
SEAL ROCK THERAPEUTICS, INC. US Patent					Assay Description The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...				US Patent US10150755 (2018) BindingDB Entry DOI: 10.7270/Q27P91GS
					More data for this Ligand-Target Pair