null

SMILES: CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C1=CCN(CC1)C(C)C

InChI Key: InChIKey=QEAUPAREISBURF-YHBQERECSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 308369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM308369 (US9649309, Compound UNC4358A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C1=CCN(CC1)C(C)C |r,wU:11.10,wD:14.14,t:28,(-10,-4.62,;-8.67,-3.85,;-7.34,-4.62,;-6,-3.85,;-4.67,-4.62,;-3.33,-3.85,;-2,-4.62,;-.67,-3.85,;-.67,-2.31,;-2,-1.54,;-2,,;-3.33,.77,;-4.67,,;-6,.77,;-6,2.31,;-7.34,3.08,;-4.67,3.08,;-3.33,2.31,;-3.33,-2.31,;.67,-1.54,;2,-2.31,;3.33,-1.54,;3.33,,;2,.77,;.67,,;4.67,.77,;4.67,2.31,;6,3.08,;7.34,2.31,;7.34,.77,;6,,;8.67,3.08,;10,2.31,;8.67,4.62,)| Show InChI InChI=1S/C27H40N6O/c1-4-5-14-28-27-30-18-24(26(32-27)31-22-7-9-23(34)10-8-22)25-11-6-21(17-29-25)20-12-15-33(16-13-20)19(2)3/h6,11-12,17-19,22-23,34H,4-5,7-10,13-16H2,1-3H3,(H2,28,30,31,32)/t22-,23-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM308369 (US9649309, Compound UNC4358A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C1=CCN(CC1)C(C)C |r,wU:11.10,wD:14.14,t:28,(-10,-4.62,;-8.67,-3.85,;-7.34,-4.62,;-6,-3.85,;-4.67,-4.62,;-3.33,-3.85,;-2,-4.62,;-.67,-3.85,;-.67,-2.31,;-2,-1.54,;-2,,;-3.33,.77,;-4.67,,;-6,.77,;-6,2.31,;-7.34,3.08,;-4.67,3.08,;-3.33,2.31,;-3.33,-2.31,;.67,-1.54,;2,-2.31,;3.33,-1.54,;3.33,,;2,.77,;.67,,;4.67,.77,;4.67,2.31,;6,3.08,;7.34,2.31,;7.34,.77,;6,,;8.67,3.08,;10,2.31,;8.67,4.62,)| Show InChI InChI=1S/C27H40N6O/c1-4-5-14-28-27-30-18-24(26(32-27)31-22-7-9-23(34)10-8-22)25-11-6-21(17-29-25)20-12-15-33(16-13-20)19(2)3/h6,11-12,17-19,22-23,34H,4-5,7-10,13-16H2,1-3H3,(H2,28,30,31,32)/t22-,23-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair
Growth arrest-specific protein 6 (Homo sapiens (Human))	BDBM308369 (US9649309, Compound UNC4358A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C1=CCN(CC1)C(C)C |r,wU:11.10,wD:14.14,t:28,(-10,-4.62,;-8.67,-3.85,;-7.34,-4.62,;-6,-3.85,;-4.67,-4.62,;-3.33,-3.85,;-2,-4.62,;-.67,-3.85,;-.67,-2.31,;-2,-1.54,;-2,,;-3.33,.77,;-4.67,,;-6,.77,;-6,2.31,;-7.34,3.08,;-4.67,3.08,;-3.33,2.31,;-3.33,-2.31,;.67,-1.54,;2,-2.31,;3.33,-1.54,;3.33,,;2,.77,;.67,,;4.67,.77,;4.67,2.31,;6,3.08,;7.34,2.31,;7.34,.77,;6,,;8.67,3.08,;10,2.31,;8.67,4.62,)| Show InChI InChI=1S/C27H40N6O/c1-4-5-14-28-27-30-18-24(26(32-27)31-22-7-9-23(34)10-8-22)25-11-6-21(17-29-25)20-12-15-33(16-13-20)19(2)3/h6,11-12,17-19,22-23,34H,4-5,7-10,13-16H2,1-3H3,(H2,28,30,31,32)/t22-,23-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM308369 (US9649309, Compound UNC4358A) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(cn1)C1=CCN(CC1)C(C)C |r,wU:11.10,wD:14.14,t:28,(-10,-4.62,;-8.67,-3.85,;-7.34,-4.62,;-6,-3.85,;-4.67,-4.62,;-3.33,-3.85,;-2,-4.62,;-.67,-3.85,;-.67,-2.31,;-2,-1.54,;-2,,;-3.33,.77,;-4.67,,;-6,.77,;-6,2.31,;-7.34,3.08,;-4.67,3.08,;-3.33,2.31,;-3.33,-2.31,;.67,-1.54,;2,-2.31,;3.33,-1.54,;3.33,,;2,.77,;.67,,;4.67,.77,;4.67,2.31,;6,3.08,;7.34,2.31,;7.34,.77,;6,,;8.67,3.08,;10,2.31,;8.67,4.62,)| Show InChI InChI=1S/C27H40N6O/c1-4-5-14-28-27-30-18-24(26(32-27)31-22-7-9-23(34)10-8-22)25-11-6-21(17-29-25)20-12-15-33(16-13-20)19(2)3/h6,11-12,17-19,22-23,34H,4-5,7-10,13-16H2,1-3H3,(H2,28,30,31,32)/t22-,23-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair