BDBM308636 BDBM308807::US9656955, Example 150::trans-N-[2-chloro-4-(trifluoromethyl)benzyl]-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-amine

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=YVZLVQWRIZHLDX-AZUAARDMSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308636 (BDBM308807 | US9656955, Example 150 | trans-N-[2-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C22H21ClF4N4O2S/c1-30-12-21(29-13-30)34(32,33)31-10-18(14-3-6-17(24)7-4-14)20(11-31)28-9-15-2-5-16(8-19(15)23)22(25,26)27/h2-8,12-13,18,20,28H,9-11H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308636 (BDBM308807 | US9656955, Example 150 | trans-N-[2-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C22H21ClF4N4O2S/c1-30-12-21(29-13-30)34(32,33)31-10-18(14-3-6-17(24)7-4-14)20(11-31)28-9-15-2-5-16(8-19(15)23)22(25,26)27/h2-8,12-13,18,20,28H,9-11H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair