BDBM308767 BDBM308881::US9656955, Example 281::trans-N-[2-chloro-4-(trifluoromethyl)benzyl]-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-phenylpyrrolidin-3-amine

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccccc1

InChI Key: InChIKey=DMDKQMSPISNBFQ-AZUAARDMSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308767 (BDBM308881 | US9656955, Example 281 | trans-N-[2-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C22H22ClF3N4O2S/c1-29-13-21(28-14-29)33(31,32)30-11-18(15-5-3-2-4-6-15)20(12-30)27-10-16-7-8-17(9-19(16)23)22(24,25)26/h2-9,13-14,18,20,27H,10-12H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308767 (BDBM308881 | US9656955, Example 281 | trans-N-[2-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C22H22ClF3N4O2S/c1-29-13-21(28-14-29)33(31,32)30-11-18(15-5-3-2-4-6-15)20(12-30)27-10-16-7-8-17(9-19(16)23)22(24,25)26/h2-9,13-14,18,20,27H,10-12H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair