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SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@@H](COc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=ZBARKLSSFJNWMD-YJBOKZPZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 308780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))		BDBM308780
PNG
(4-{[trans-3-{[2-chloro-4-(trifluoromethyl)phenoxy]...)
Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](COc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1
Show InChI InChI=1S/C22H20ClF4N3O3S/c1-29-11-21(28-13-29)34(31,32)30-9-15(18(10-30)14-2-5-17(24)6-3-14)12-33-20-7-4-16(8-19(20)23)22(25,26)27/h2-8,11,13,15,18H,9-10,12H2,1H3/t15-,18-/m0/s1
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PC cid
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US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...

US Patent US9656955 (2017)


BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair