BDBM309199 N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}-6-phenylpyrimidin-4-amin::US9656955, Example 722

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccccc2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=FSKZYBVEKFZRRB-IRLDBZIGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309199 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccccc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN6O2S/c1-30-14-24(28-16-30)34(32,33)31-12-20(17-7-9-19(25)10-8-17)22(13-31)29-23-11-21(26-15-27-23)18-5-3-2-4-6-18/h2-11,14-16,20,22H,12-13H2,1H3,(H,26,27,29)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair