BDBM309202 N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}-6-(4-methylphenyl)pyrimidin-4-amine::US9656955, Example 725

SMILES: Cc1ccc(cc1)-c1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ncn1

InChI Key: InChIKey=CUIAJPPZPMJIKB-GGAORHGYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309202 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) Show SMILES Cc1ccc(cc1)-c1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ncn1 Show InChI InChI=1S/C25H25FN6O2S/c1-17-3-5-19(6-4-17)22-11-24(28-15-27-22)30-23-13-32(35(33,34)25-14-31(2)16-29-25)12-21(23)18-7-9-20(26)10-8-18/h3-11,14-16,21,23H,12-13H2,1-2H3,(H,27,28,30)/t21-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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