BDBM309205 6-(4-fluorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}pyrimidin-4-amine::US9656955, Example 728

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccc(F)cc2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=WUZBSEFBBJLNFF-IRLDBZIGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309205 (6-(4-fluorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccc(F)cc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22F2N6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-20(16-2-6-18(25)7-3-16)22(12-32)30-23-10-21(27-14-28-23)17-4-8-19(26)9-5-17/h2-10,13-15,20,22H,11-12H2,1H3,(H,27,28,30)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair