BDBM309210 (3R,4S)-N-(2,2-difluorohexyl)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-amine::US9656955, Example 733

SMILES: CCCCC(F)(F)CN[C@H]1CN(C[C@@H]1c1ccc(F)cc1)S(=O)(=O)c1cn(C)cn1

InChI Key: InChIKey=KKMSUWHCAMWWTH-MSOLQXFVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309210 ((3R,4S)-N-(2,2-difluorohexyl)-4-(4-fluorophenyl)-1...) Show SMILES CCCCC(F)(F)CN[C@H]1CN(C[C@@H]1c1ccc(F)cc1)S(=O)(=O)c1cn(C)cn1 Show InChI InChI=1S/C20H27F3N4O2S/c1-3-4-9-20(22,23)13-24-18-11-27(30(28,29)19-12-26(2)14-25-19)10-17(18)15-5-7-16(21)8-6-15/h5-8,12,14,17-18,24H,3-4,9-11,13H2,1-2H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair