BDBM309236 4-chloro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}pyridin-2-amine::US9656955, Example 759

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(Cl)ccn2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=GWMJCJQVZKKACT-SJORKVTESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309236 (4-chloro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(Cl)ccn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H19ClFN5O2S/c1-25-11-19(23-12-25)29(27,28)26-9-16(13-2-4-15(21)5-3-13)17(10-26)24-18-8-14(20)6-7-22-18/h2-8,11-12,16-17H,9-10H2,1H3,(H,22,24)/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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