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SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(c(F)cn2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=LADXIHGAZFPQDL-PBHICJAKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309272   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))		BDBM309272
PNG
(5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...)
Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(c(F)cn2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1
Show InChI InChI=1S/C20H18F5N5O2S/c1-29-10-19(27-11-29)33(31,32)30-8-14(12-2-4-13(21)5-3-12)17(9-30)28-18-6-15(20(23,24)25)16(22)7-26-18/h2-7,10-11,14,17H,8-9H2,1H3,(H,26,28)/t14-,17+/m1/s1
PDB
MMDB

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PC cid
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US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...

US Patent US9656955 (2017)


BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair