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SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccccc1

InChI Key: InChIKey=VYMUHSBFBPGJTC-WBVHZDCISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309280   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))		BDBM309280
PNG
(5-fluoro-N-{(3R,4S)-1-[(1-methyl-1H-imidazol-4-yl)...)
Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccccc1
Show InChI InChI=1S/C21H21F4N5O3S/c1-29-11-20(27-13-29)34(31,32)30-9-15(14-5-3-2-4-6-14)17(10-30)28-19-7-18(16(22)8-26-19)33-12-21(23,24)25/h2-8,11,13,15,17H,9-10,12H2,1H3,(H,26,28)/t15-,17+/m1/s1
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PC cid
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US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...

US Patent US9656955 (2017)


BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair