BDBM309286 5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}-4-(2,2,2-trifluoroethoxy)pyridin-2-amine::US9656955, Example 810

SMILES: Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=VHHCJDIPTONXFE-WBVHZDCISA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309286 (5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20F5N5O3S/c1-30-10-20(28-12-30)35(32,33)31-8-15(13-2-4-14(22)5-3-13)17(9-31)29-19-6-18(16(23)7-27-19)34-11-21(24,25)26/h2-7,10,12,15,17H,8-9,11H2,1H3,(H,27,29)/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair