BDBM309317 (3R,4S)-N-(3-chloro-4-fluorophenyl)-4-(4-fluorophenyl)-1-[(1-methyl-1H-1,2,3-triazol-4-yl)sulfonyl]pyrrolidin-3-amine::US9656955, Example 842

SMILES: Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(Cl)c2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=WEENHDWGDCHBLX-QAPCUYQASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309317 ((3R,4S)-N-(3-chloro-4-fluorophenyl)-4-(4-fluorophe...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(Cl)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H18ClF2N5O2S/c1-26-11-19(24-25-26)30(28,29)27-9-15(12-2-4-13(21)5-3-12)18(10-27)23-14-6-7-17(22)16(20)8-14/h2-8,11,15,18,23H,9-10H2,1H3/t15-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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