BDBM309429 (2S,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(2,4-dichlorobenzyl)-3a,8-dihydroxy- 1,2,3,3a,4,5-hexahydro-4,9b-(epimino- ethano)cyclopenta[a]naphthalene-2- carboxamide::US9656962, Compound 45
SMILES: Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@@H](C[C@@]34O)C(=O)NCc3ccc(Cl)cc3Cl)c2c1
InChI Key: InChIKey=WSLIEDMZWMXUFX-ISCKJPLLSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM309429 ((2S,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(2,4-dic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a |
Purdue Pharma L.P. US Patent | Assay Description δ-Opioid Receptor Binding Assay Procedures: δ-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displace... | US Patent US9656962 (2017) BindingDB Entry DOI: 10.7270/Q2K076BH | |||||||||||
More data for this Ligand-Target Pair |