BDBM309492 US9603833, Example 114

SMILES: CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(CNC(=O)NN)cc2F)nc1

InChI Key: InChIKey=IWSUDBRWTUJSQX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase, copper containing (Rattus norvegicus (Rat))	BDBM309492 (US9603833, Example 114) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(CNC(=O)NN)cc2F)nc1 Show InChI InChI=1S/C21H27FN6O2/c1-15(29)27-8-10-28(11-9-27)19-7-6-18(24-14-19)5-4-17-3-2-16(12-20(17)22)13-25-21(30)26-23/h2-3,6-7,12,14H,4-5,8-11,13,23H2,1H3,(H2,25,26,30)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human))	BDBM309492 (US9603833, Example 114) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(CNC(=O)NN)cc2F)nc1 Show InChI InChI=1S/C21H27FN6O2/c1-15(29)27-8-10-28(11-9-27)19-7-6-18(24-14-19)5-4-17-3-2-16(12-20(17)22)13-25-21(30)26-23/h2-3,6-7,12,14H,4-5,8-11,13,23H2,1H3,(H2,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair