null
SMILES: CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
InChI Key: InChIKey=WVUNYSQLFKLYNI-AATRIKPKSA-N
PDB links: 2 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Yes (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2PN940F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 25 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JW8C8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21Z42S7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2X63K98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2SF2TJ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity mitogen-activated protein kinase kinase 2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NP22TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2MG7MVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GQ6W41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase DCLK3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2H130D4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 17A (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C827PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27H1GZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q22R3Q13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NUAK family SNF1-like kinase 2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2Z036J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 5 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C24TSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Mer (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q279432J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23J3BBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2Q81BDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KH0KP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2TB158J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BMP-2-inducible protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2F18X3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q29885C6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 17B (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2X34VTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q24J0CHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
STE20-like serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25B00TC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase MARK1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20V8B5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GT5KJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 24 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23N21SK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Nek2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QC01W0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2XW4H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 33 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J983H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor Tie-1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2WS8RKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase SIK2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2S46Q94 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q24F1P4S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Wee1-like protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20P0XD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Atypical kinase COQ8B, mitochondrial (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2MG7MWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytoplasmic tyrosine-protein kinase BMX (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GQ6W5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BZ64F4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase TXK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2TX3CRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myotonin-protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2668BJW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB PCBioAssay | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2XP739T | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activated CDC42 kinase 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2T1521K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2P8499V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JH3JK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha-like (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2DR2SVD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Nek1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.90E+6 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q290224S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PAK 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25719D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 32B (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BV7DZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2736P7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23B5XHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair |
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