BDBM311438 CHEM-US-00135::US10155764, Example 26

SMILES: CN(C)C(CNc1nn(C)c(=O)c2ccccc12)c1ccccc1F

InChI Key: InChIKey=NHHODRQTZBHNSR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311438 (CHEM-US-00135 | US10155764, Example 26) Show SMILES CN(C)C(CNc1nn(C)c(=O)c2ccccc12)c1ccccc1F Show InChI InChI=1S/C19H21FN4O/c1-23(2)17(15-10-6-7-11-16(15)20)12-21-18-13-8-4-5-9-14(13)19(25)24(3)22-18/h4-11,17H,12H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair