null

SMILES: CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1

InChI Key: InChIKey=UGPZFEUGECMRRH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 311444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311444 (CHEM-US-00141 | US10155764, Example 32 | US1015576...) Show SMILES CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H25ClN6O/c1-26(2)18-13-28(15-8-6-14(22)7-9-15)12-10-17(18)24-20-19-16(5-4-11-23-19)21(29)27(3)25-20/h4-9,11,17-18H,10,12-13H2,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311444 (CHEM-US-00141 | US10155764, Example 32 | US1015576...) Show SMILES CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H25ClN6O/c1-26(2)18-13-28(15-8-6-14(22)7-9-15)12-10-17(18)24-20-19-16(5-4-11-23-19)21(29)27(3)25-20/h4-9,11,17-18H,10,12-13H2,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311444 (CHEM-US-00141 | US10155764, Example 32 | US1015576...) Show SMILES CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H25ClN6O/c1-26(2)18-13-28(15-8-6-14(22)7-9-15)12-10-17(18)24-20-19-16(5-4-11-23-19)21(29)27(3)25-20/h4-9,11,17-18H,10,12-13H2,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair