BDBM31153 3-hydroxyquinolin-2(1H)-one, 7
SMILES: Oc1cc2cccc(Cl)c2[nH]c1=O
InChI Key: InChIKey=VGEABQRORWAAST-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM31153 (3-hydroxyquinolin-2(1H)-one, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | 8.5 | 22 |
Pfizer | Assay Description Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox... | J Med Chem 52: 3576-85 (2009) Article DOI: 10.1021/jm900128w BindingDB Entry DOI: 10.7270/Q2CZ35HM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
D-amino-acid oxidase (Rattus norvegicus (rat)) | BDBM31153 (3-hydroxyquinolin-2(1H)-one, 7) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox... | J Med Chem 52: 3576-85 (2009) Article DOI: 10.1021/jm900128w BindingDB Entry DOI: 10.7270/Q2CZ35HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-aspartate oxidase (Homo sapiens (Human)) | BDBM31153 (3-hydroxyquinolin-2(1H)-one, 7) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >4.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke... | J Med Chem 52: 3576-85 (2009) Article DOI: 10.1021/jm900128w BindingDB Entry DOI: 10.7270/Q2CZ35HM | |||||||||||
More data for this Ligand-Target Pair |