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BDBM31159 3-hydroxyquinolin-2(1H)-one, 13

SMILES: Cc1ccc2[nH]c(=O)c(O)cc2c1

InChI Key: InChIKey=HHBIREFHPDVOQC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31159   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM31159
PNG
(3-hydroxyquinolin-2(1H)-one, 13)
Show SMILES Cc1ccc2[nH]c(=O)c(O)cc2c1
Show InChI InChI=1S/C10H9NO2/c1-6-2-3-8-7(4-6)5-9(12)10(13)11-8/h2-5,12H,1H3,(H,11,13)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.75E+3n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


J Med Chem 52: 3576-85 (2009)


Article DOI: 10.1021/jm900128w
BindingDB Entry DOI: 10.7270/Q2CZ35HM
More data for this
Ligand-Target Pair
3D
3D Structure (docked)