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BDBM31162 3-hydroxyquinolin-2(1H)-one, 16

SMILES: CCc1ccc2cc(O)c(=O)[nH]c2c1

InChI Key: InChIKey=AOGSDHLADKKXMJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31162   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM31162
PNG
(3-hydroxyquinolin-2(1H)-one, 16)
Show SMILES CCc1ccc2cc(O)c(=O)[nH]c2c1
Show InChI InChI=1S/C11H11NO2/c1-2-7-3-4-8-6-10(13)11(14)12-9(8)5-7/h3-6,13H,2H2,1H3,(H,12,14)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.26E+4n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


J Med Chem 52: 3576-85 (2009)


Article DOI: 10.1021/jm900128w
BindingDB Entry DOI: 10.7270/Q2CZ35HM
More data for this
Ligand-Target Pair