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BDBM31163 3-hydroxyquinolin-2(1H)-one, 17

SMILES: CCc1cccc2cc(O)c(=O)[nH]c12

InChI Key: InChIKey=YIHATGASCZDYBB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31163   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-Aspartate Oxidase (DDO)


(Homo sapiens (Human))
BDBM31163
PNG
(3-hydroxyquinolin-2(1H)-one, 17)
Show SMILES CCc1cccc2cc(O)c(=O)[nH]c12
Show InChI InChI=1S/C11H11NO2/c1-2-7-4-3-5-8-6-9(13)11(14)12-10(7)8/h3-6,13H,2H2,1H3,(H,12,14)
KEGG

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...


J Med Chem 52: 3576-85 (2009)


Article DOI: 10.1021/jm900128w
BindingDB Entry DOI: 10.7270/Q2CZ35HM
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM31163
PNG
(3-hydroxyquinolin-2(1H)-one, 17)
Show SMILES CCc1cccc2cc(O)c(=O)[nH]c12
Show InChI InChI=1S/C11H11NO2/c1-2-7-4-3-5-8-6-9(13)11(14)12-10(7)8/h3-6,13H,2H2,1H3,(H,12,14)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.44E+4n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


J Med Chem 52: 3576-85 (2009)


Article DOI: 10.1021/jm900128w
BindingDB Entry DOI: 10.7270/Q2CZ35HM
More data for this
Ligand-Target Pair