BDBM311904 US10166214, Example 40::US10675268, Example 40::US9789082, Example 40

SMILES: Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12

InChI Key: InChIKey=FSMVCTXWSBPYPY-NHAGDIPZSA-N

Data: 15 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 311904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>8.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>8.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>8.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>9.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...				US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM311904 (US10166214, Example 40 | US10675268, Example 40 | ...) Show SMILES Cc1ccccc1OCC(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r| Show InChI InChI=1S/C17H24N2O2/c1-11-6-4-5-7-14(11)21-10-17(2,3)19-16(20)15-12-8-18-9-13(12)15/h4-7,12-13,15,18H,8-10H2,1-3H3,(H,19,20)/t12-,13+,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...				US Patent US10675268 (2020)
					More data for this Ligand-Target Pair