BDBM312138 6-hydroxy-2-(4-hydroxyphenol)-4-(4-methoxyphenyl)isoquinolin-1(2H)-one::US9604931, 15b
SMILES: COc1ccc(cc1)-c1cn(-c2ccc(O)cc2)c(=O)c2ccc(O)cc12
InChI Key: InChIKey=BVCSBABZBDLYNM-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid hormone receptor ERR2 (Homo sapiens (Human)) | BDBM312138 (6-hydroxy-2-(4-hydroxyphenol)-4-(4-methoxyphenyl)i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent | Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr... | US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM312138 (6-hydroxy-2-(4-hydroxyphenol)-4-(4-methoxyphenyl)i...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent | Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr... | US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR | |||||||||||
More data for this Ligand-Target Pair |