null
SMILES: Oc1ccc(cc1)-n1cc(-c2ccccc2)c2cc(O)cc(O)c2c1=O
InChI Key: InChIKey=UQJVSWJIGSWDBK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid hormone receptor ERR2 (Homo sapiens (Human)) | BDBM312149 (6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.03 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent | Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr... | US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM312149 (6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.03 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTX, Inc. US Patent | Assay Description Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4... | US Patent US9623021 (2017) BindingDB Entry DOI: 10.7270/Q20C4XV9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM312149 (6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTX, Inc. US Patent | Assay Description Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4... | US Patent US9623021 (2017) BindingDB Entry DOI: 10.7270/Q20C4XV9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM312149 (6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent | Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr... | US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR | |||||||||||
More data for this Ligand-Target Pair |