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SMILES: C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12

InChI Key: InChIKey=QAGWYKCFYYZWRQ-NSCUHMNNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid hormone receptor ERR2 (Homo sapiens (Human))	BDBM312151 ((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...) Show SMILES C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12 Show InChI InChI=1S/C18H15NO4/c1-2-3-11-10-19(12-4-6-13(20)7-5-12)18(23)17-15(11)8-14(21)9-16(17)22/h2-10,20-22H,1H3/b3-2+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent					Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...				US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM312151 ((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...) Show SMILES C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12 Show InChI InChI=1S/C18H15NO4/c1-2-3-11-10-19(12-4-6-13(20)7-5-12)18(23)17-15(11)8-14(21)9-16(17)22/h2-10,20-22H,1H3/b3-2+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTX, Inc. US Patent					Assay Description Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...				US Patent US9623021 (2017) BindingDB Entry DOI: 10.7270/Q20C4XV9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM312151 ((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...) Show SMILES C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12 Show InChI InChI=1S/C18H15NO4/c1-2-3-11-10-19(12-4-6-13(20)7-5-12)18(23)17-15(11)8-14(21)9-16(17)22/h2-10,20-22H,1H3/b3-2+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTX, Inc. US Patent					Assay Description Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...				US Patent US9623021 (2017) BindingDB Entry DOI: 10.7270/Q20C4XV9
					More data for this Ligand-Target Pair
Steroid hormone receptor ERR1 (Homo sapiens (Human))	BDBM312151 ((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...) Show SMILES C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12 Show InChI InChI=1S/C18H15NO4/c1-2-3-11-10-19(12-4-6-13(20)7-5-12)18(23)17-15(11)8-14(21)9-16(17)22/h2-10,20-22H,1H3/b3-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS US Patent					Assay Description Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...				US Patent US9604931 (2017) BindingDB Entry DOI: 10.7270/Q23N25FR
					More data for this Ligand-Target Pair