BDBM312231 US9604926, Compound AZ-59::US9724435, Compound AZ-59

SMILES: CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1

InChI Key: InChIKey=VUBGRMFNMXNMMF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-2 receptor (Rattus norvegicus (Rat))	BDBM312231 (US9604926, Compound AZ-59 | US9724435, Compound AZ...) Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C22H33N3S2/c1-18(23-14-16-24(17-15-23)19-9-3-2-4-10-19)8-7-13-25-20-11-5-6-12-21(20)27-22(25)26/h5-6,11-12,18-19H,2-4,7-10,13-17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Mus musculus (Mouse))	BDBM312231 (US9604926, Compound AZ-59 | US9724435, Compound AZ...) Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C22H33N3S2/c1-18(23-14-16-24(17-15-23)19-9-3-2-4-10-19)8-7-13-25-20-11-5-6-12-21(20)27-22(25)26/h5-6,11-12,18-19H,2-4,7-10,13-17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse))	BDBM312231 (US9604926, Compound AZ-59 | US9724435, Compound AZ...) Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C22H33N3S2/c1-18(23-14-16-24(17-15-23)19-9-3-2-4-10-19)8-7-13-25-20-11-5-6-12-21(20)27-22(25)26/h5-6,11-12,18-19H,2-4,7-10,13-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM312231 (US9604926, Compound AZ-59 | US9724435, Compound AZ...) Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C22H33N3S2/c1-18(23-14-16-24(17-15-23)19-9-3-2-4-10-19)8-7-13-25-20-11-5-6-12-21(20)27-22(25)26/h5-6,11-12,18-19H,2-4,7-10,13-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair