BDBM31225 2-phenoxybenzoyltryptophan derivative, R5C3
SMILES: Cc1ccc2n(cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(O)=O)c2c1)C(=O)OCc1ccccc1
InChI Key: InChIKey=FHNQOOZTZWBWQO-NDEPHWFRSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDM2-MDMX (Homo sapiens (Human)) | BDBM31225 (2-phenoxybenzoyltryptophan derivative, R5C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 100 | -9.48 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
More data for this Ligand-Target Pair |