null

SMILES: C[C@@H]1Cc2c(C1)n(nc2C(N)=O)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O

InChI Key: InChIKey=LOMJXQYGZQMNMM-ASSNKEHSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM312904 ((5R)-1-[3-[2-[(3R)-3-hydroxy- 1-methyl-2-oxo-pyrro...) Show SMILES C[C@@H]1Cc2c(C1)n(nc2C(N)=O)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O |r| Show InChI InChI=1S/C21H22N4O3/c1-13-10-16-17(11-13)25(23-18(16)19(22)26)15-5-3-4-14(12-15)6-7-21(28)8-9-24(2)20(21)27/h3-5,12-13,28H,8-11H2,1-2H3,(H2,22,26)/t13-,21+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...				US Patent US9605005 (2017) BindingDB Entry DOI: 10.7270/Q2T43W61
					More data for this Ligand-Target Pair