Found 3 hits for monomerid = 313756 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM313756
(US10167285, Example (2exp))Show SMILES Cc1ncc2NC(Sc3c(Br)ccc(Cl)c3Cl)N(CCCC#C)c2n1 Show InChI InChI=1S/C17H15BrCl2N4S/c1-3-4-5-8-24-16-13(9-21-10(2)22-16)23-17(24)25-15-11(18)6-7-12(19)14(15)20/h1,6-7,9,17,23H,4-5,8H2,2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 50.8 | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| Assay Description The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ... |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313756
(US10167285, Example (2exp))Show SMILES Cc1ncc2NC(Sc3c(Br)ccc(Cl)c3Cl)N(CCCC#C)c2n1 Show InChI InChI=1S/C17H15BrCl2N4S/c1-3-4-5-8-24-16-13(9-21-10(2)22-16)23-17(24)25-15-11(18)6-7-12(19)14(15)20/h1,6-7,9,17,23H,4-5,8H2,2H3 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313756
(US10167285, Example (2exp))Show SMILES Cc1ncc2NC(Sc3c(Br)ccc(Cl)c3Cl)N(CCCC#C)c2n1 Show InChI InChI=1S/C17H15BrCl2N4S/c1-3-4-5-8-24-16-13(9-21-10(2)22-16)23-17(24)25-15-11(18)6-7-12(19)14(15)20/h1,6-7,9,17,23H,4-5,8H2,2H3 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 365 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |