Found 3 hits for monomerid = 313757 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM313757
(US10167285, Example 2)Show InChI InChI=1S/C16H13Cl3N4S/c1-2-3-4-7-23-15-12(8-20-9-21-15)22-16(23)24-14-11(18)6-5-10(17)13(14)19/h1,5-6,8-9,16,22H,3-4,7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| Assay Description The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ... |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313757
(US10167285, Example 2)Show InChI InChI=1S/C16H13Cl3N4S/c1-2-3-4-7-23-15-12(8-20-9-21-15)22-16(23)24-14-11(18)6-5-10(17)13(14)19/h1,5-6,8-9,16,22H,3-4,7H2 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313757
(US10167285, Example 2)Show InChI InChI=1S/C16H13Cl3N4S/c1-2-3-4-7-23-15-12(8-20-9-21-15)22-16(23)24-14-11(18)6-5-10(17)13(14)19/h1,5-6,8-9,16,22H,3-4,7H2 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |