Found 3 hits for monomerid = 313761 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM313761
(US10167285, Example 6)Show InChI InChI=1S/C17H15BrN4O/c1-2-3-4-7-22-15(21-13-9-19-10-20-17(13)22)8-11-12(18)5-6-14-16(11)23-14/h1,5-6,9-10,15,21H,3-4,7-8H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 56.5 | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| Assay Description The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ... |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313761
(US10167285, Example 6)Show InChI InChI=1S/C17H15BrN4O/c1-2-3-4-7-22-15(21-13-9-19-10-20-17(13)22)8-11-12(18)5-6-14-16(11)23-14/h1,5-6,9-10,15,21H,3-4,7-8H2 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM313761
(US10167285, Example 6)Show InChI InChI=1S/C17H15BrN4O/c1-2-3-4-7-22-15(21-13-9-19-10-20-17(13)22)8-11-12(18)5-6-14-16(11)23-14/h1,5-6,9-10,15,21H,3-4,7-8H2 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Memorial Sloan Kettering Cancer Center
US Patent
| |
US Patent US10167285 (2019)
BindingDB Entry DOI: 10.7270/Q2BZ684R |
More data for this Ligand-Target Pair | |