BDBM314198 (S)-2-(5,5-bis(4-fluorophenyl)-2-oxo-4-phenyloxazolidin-3-yl)acetamide::US9611232, Example 1

SMILES: NC(=O)CN1[C@@H](c2ccccc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=ONEZXVWCRQOWCI-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM314198 ((S)-2-(5,5-bis(4-fluorophenyl)-2-oxo-4-phenyloxazo...) Show SMILES NC(=O)CN1[C@@H](c2ccccc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H18F2N2O3/c24-18-10-6-16(7-11-18)23(17-8-12-19(25)13-9-17)21(15-4-2-1-3-5-15)27(14-20(26)28)22(29)30-23/h1-13,21H,14H2,(H2,26,28)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...				US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM
					More data for this Ligand-Target Pair