BDBM314215 US9611232, Example 7

SMILES: NC(=O)CN1[C@@H](c2ccc(F)cc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=XWNOUAOTNUVPPW-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM314215 (US9611232, Example 7) Show SMILES NC(=O)CN1[C@@H](c2ccc(F)cc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H17F3N2O3/c24-17-7-1-14(2-8-17)21-23(15-3-9-18(25)10-4-15,16-5-11-19(26)12-6-16)31-22(30)28(21)13-20(27)29/h1-12,21H,13H2,(H2,27,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...				US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM
					More data for this Ligand-Target Pair