BDBM314248 US9611232, Example 13

SMILES: NC(=O)CN1[C@@H](c2ccccc2F)C(OC1=O)(c1ccccc1F)c1ccccc1F

InChI Key: InChIKey=CWMDJCGLICPBMZ-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM314248 (US9611232, Example 13) Show SMILES NC(=O)CN1[C@@H](c2ccccc2F)C(OC1=O)(c1ccccc1F)c1ccccc1F |r| Show InChI InChI=1S/C23H17F3N2O3/c24-17-10-4-1-7-14(17)21-23(15-8-2-5-11-18(15)25,16-9-3-6-12-19(16)26)31-22(30)28(21)13-20(27)29/h1-12,21H,13H2,(H2,27,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...				US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM
					More data for this Ligand-Target Pair