BDBM314288 US9611232, Example 19
SMILES: NC(=O)CN1[C@@H](c2ccccc2Cl)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
InChI Key: InChIKey=DMUBQSIUQZPUTR-NRFANRHFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human)) | BDBM314288 (US9611232, Example 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp... | US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM | |||||||||||
More data for this Ligand-Target Pair |