BDBM314321 US9611232, Example 32

SMILES: CCOC(=O)CN1[C@@H]([C@@H](OC1=O)c1cccc(c1)C(F)(F)F)c1ccc(F)cc1

InChI Key: InChIKey=GDKSAHVNUWPRRT-MSOLQXFVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM314321 (US9611232, Example 32) Show SMILES CCOC(=O)CN1[C@@H]([C@@H](OC1=O)c1cccc(c1)C(F)(F)F)c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H17F4NO4/c1-2-28-16(26)11-25-17(12-6-8-15(21)9-7-12)18(29-19(25)27)13-4-3-5-14(10-13)20(22,23)24/h3-10,17-18H,2,11H2,1H3/t17-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...				US Patent US9611232 (2017) BindingDB Entry DOI: 10.7270/Q2P84DZM
					More data for this Ligand-Target Pair