BDBM316210 5-(6-(2-methoxyphenyl)pyrimidin-4-ylamino)-2-(4-methylpiperazin-1-yl)benzenesulfonamide::US10294218, Example 38::US9617225, Example 38

SMILES: COc1ccccc1-c1cc(Nc2ccc(N3CCN(C)CC3)c(c2)S(N)(=O)=O)ncn1

InChI Key: InChIKey=BVIPBFLBEVHPIW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human))	BDBM316210 (5-(6-(2-methoxyphenyl)pyrimidin-4-ylamino)-2-(4-me...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(N3CCN(C)CC3)c(c2)S(N)(=O)=O)ncn1 Show InChI InChI=1S/C22H26N6O3S/c1-27-9-11-28(12-10-27)19-8-7-16(13-21(19)32(23,29)30)26-22-14-18(24-15-25-22)17-5-3-4-6-20(17)31-2/h3-8,13-15H,9-12H2,1-2H3,(H2,23,29,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316210 (5-(6-(2-methoxyphenyl)pyrimidin-4-ylamino)-2-(4-me...) Show SMILES COc1ccccc1-c1cc(Nc2ccc(N3CCN(C)CC3)c(c2)S(N)(=O)=O)ncn1 Show InChI InChI=1S/C22H26N6O3S/c1-27-9-11-28(12-10-27)19-8-7-16(13-21(19)32(23,29)30)26-22-14-18(24-15-25-22)17-5-3-4-6-20(17)31-2/h3-8,13-15H,9-12H2,1-2H3,(H2,23,29,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair